Voriconazole Therapeutic Drug Monitoring

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منابع مشابه

Voriconazole therapeutic drug monitoring.

We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.

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Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring : A Multi - Center Study

Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring: A Multi-Center Study 1 2 Michael J Dolton, John E Ray, Sharon C-A Chen, Kingsley Ng, Lisa G Pont, Andrew J 3 McLachlan 4 5 1 Faculty of Pharmacy, University of Sydney, Camperdown, Australia 6 2 Clinical Pharmacology & Toxicology, SydPath, St Vincent’s Hospital, Darlinghurst, 7 Australia 8 3 Centre for Infectious Diseases & Microbiol...

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Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring : A Multi

Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring: A Multi-Center Study 1 2 Michael J Dolton, John E Ray, Sharon C-A Chen, Kingsley Ng, Lisa G Pont, Andrew J 3 McLachlan 4 5 1 Faculty of Pharmacy, University of Sydney, Camperdown, Australia 6 2 Clinical Pharmacology & Toxicology, SydPath, St Vincent’s Hospital, Darlinghurst, 7 Australia 8 3 Centre for Infectious Diseases & Microbiol...

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Successful management of voriconazole-associated hyponatremia with therapeutic drug monitoring.

Voriconazole is a broad-spectrum triazole antifungal agent and the first-choice therapy for invasive aspergillosis (IA) (1). Although voriconazole is generally well tolerated, anecdotal case reports have described unexpected severe adverse events related to voriconazole, such as hyponatremia, which potentially could result in death (2–4). We report a case of successful voriconazole treatment of...

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Voriconazole Therapeutic Drug Monitoring Practices in Intensive Care.

BACKGROUND Routine therapeutic drug monitoring of voriconazole seems to be beneficial. This study investigated the therapeutic drug monitoring practices in intensive care to derive possible recommendations for improvement. METHODS A retrospective chart review was performed for patients aged ≥18 years who started treatment with voriconazole, which lasted for at least 3 days while being admitte...

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ژورنال

عنوان ژورنال: Journal of the Pediatric Infectious Diseases Society

سال: 2014

ISSN: 2048-7193,2048-7207

DOI: 10.1093/jpids/piu019